Build strong and healthy nails.

Nuvail™ (poly-ureaurethane, 16%) is a unique, patented polymer that leaves a breathable, elegant, invisible film when applied to nails. Nuvail is indicated for managing signs and symptoms of nail dystrophy, i.e., nail splitting and nail fragility, for intact or damaged nails.

Nuvail coats and adheres to the nail surface preventing direct abrasion and friction on the nail surface while also providing protection against the effects of moisture.

About Nuvail

  • nuvail_bottle-and-swabNuvail is best applied once a day at bedtime. Nuvail is easy and convenient to use. Because Nuvail quickly dries with a clear matte finish, Nuvail looks great on women and men alike.
  • Nail polish may be worn on top of Nuvail. Do not apply polish until Nuvail is completely dry. Polish must be removed before the next application of Nuvail.
  • Nuvail is available by prescription only.

Common Symptoms of Damaged Nails²


Millions of people struggle with nail dystrophy, a nail health issue affecting both the appearance and structure of the fingernails and toenails. Nail dystrophy can cause the nails to become hard, brittle and discolored. It can also result in the nails splitting, peeling or flaking off in layers. If left untreated, the condition is uncomfortable, inconvenient and aesthetically unappealing.

Fortunately, those living with brittle nails have treatment options that can reduce and, in some cases, even eliminate the negative effects of nail dystrophy.


Healthy Nails At A Glance³


Healthy nails are composed of a series of layers that are bound together by natural protein and oil adhesives. Healthy nails are defined by their translucent, pink appearance and smooth texture. Healthy nails also consist of a closely meshed fingernail plate and nail bed, where the nail plate is the thin, hard part of the nail and the nail bed is the slotted area of the finger or toe where the plate sits.

Healthy nails are hardy, tough and don’t break easily. They don’t scratch easily on the surface, nor are they painful when they make mild contact with a hard surface. Additionally, they don’t embarrass you when you go out in public due to their chalky or discolored appearance.

If your nails don’t exhibit the characteristics of ideal nail health, you may be suffering from brittle nail syndrome, a common condition affecting approximately 20 percent of the population.

If you’ve long suffered from brittle, dry or flaky fingernails, it may be time to talk to a doctor about addressing the problem.


Common Nail Health Problems³

Onychoschizia (i.e. onychoschisis or lamellar dystrophy) is the condition that causes horizontal splits within the nail plate, while onychorrhexis is the condition that causes lengthwise splitting or ridging of the nail. The two conditions are often seen together in individuals with hard, flaking or split nails.

People who suffer from onychoschizia, onychorrhexis or both are commonly considered to have “brittle nail syndrome.”


Some undesirable traits associated with dystrophic nails include:

  • Rough, grooved or uneven fingernail plate surfaces
  • Brittle, fragile nails that chip easily
  • Nails that split – either in cases where the nail bed splits from the nail plate, or when the nail plate splits lengthwise towards the base of the nail
  • Discolored or otherwise aesthetically unappealing fingernails
  • Damaged nails appearing to be in need of repair


Why Unhealthy Nails Are a Problem³

Fragile nails are often unsightly, and patients frequently cite this as single most problematic aspect of their condition. Nail dystrophy is often associated with pain in the nail beds and nail folds of affected nails. The pain can be excruciating enough in some patients that it affects their daily activities, at times even hindering their ability to perform their jobs.

The effects of dystrophic nails can weigh heavily on the mind of the patient, who may alter their social interactions for fear of being judged for their brittle nails. Likewise, the prospect of ongoing pain in the fingers/toes and nails can put a damper on an otherwise outgoing person’s daily life.

Consulting with a Nail Health Professional¹

An experienced doctor can help you treat your weak nails. They know the nuances associated with nail dystrophy, what to look for and how to correct the damage. They can also help you avoid common mistakes those suffering from brittle nails make early in the process (i.e. applying nail hardener).

If your condition is severe enough that conventional or over-the-counter treatment methods don’t work, a doctor can write for a prescription formulated specifically for brittle nails.



Additional damaged nail resources:



  1. Nuvail™ (poly-ureaurethane, 16%) NAIL SOULTION Prescribing Information. Innocutis, Charleston, SC, 29401 USA; June 2012.
  2. Patients Guide (no date). Brittle Nail Basics (Nail Dystrophy weblog) retrieved on December 4, 2015, from http://www.patientsguide.com/conditions/nail-dystrophy/
  3. van de Kirkhof Peter CM, et al. Brittle nail syndrome: A pathogenesis-based approach with a proposed grading system. J Am Acad Dermatol 2005;53:644-51.


Nuvail™ (poly-ureaurethane, 16%) NAIL SOLUTION is indicated for managing signs and symptoms of nail dystrophy, i.e., nail splitting and nail fragility, for intact or damaged nails. Nuvail coats and adheres to the nail surface preventing direct abrasion and friction on the nail surface while also providing protection against the effects of moisture.


Do not apply directly to deep, open, or profusely bleeding wounds. Product is flammable in liquid form; avoid using near open flames and sources of ignition. Use in a well-ventilated area.

Keep out of reach of children.

Store at room temperature away from heat. Do not allow product to come into contact with floors, counter tops, furniture or other finished surfaces – will stain. May temporarily sting upon application. Persons sensitized to isocyanate should not use this product. Should redness or other signs of irritation appear, discontinue use and consult your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/Safety/MedWatch/default.htm or call 1-800-FDA-1088.

Click here for Full Prescribing Information.