Build strong and healthy nails with Nuvail

Identify the real culprit: Nail Dystrophy


  • Can be caused by trauma, disease or excessive hand washing
  • Changes the architecture of a healthy nail structure
  • Inhibits the proper function of a healthy nail
  • Exposes nails to infection
  • Gives nails an unsightly appearance

Fill In the Gaps


  • Pro: Nail plate is reduced
  • Cons: Does not treat the infection and damaged nail may be susceptible to reinfection
  • Nuvail serves as a protective sealant for a debrided nail.²


  • Pro: Treat the infection
  • Cons: Does not address underlying nail dystrophy
  • Nuvail improves the structure, function and overall look of the nail.²



60% of patients treated with Nuvail showed improvement in total visual assessments after 6 months.



A patient’s nail continues to show improvement with no recurrence of infection, even 6 months after treatment.2,3

Characteristics assessed:

  • Color
  • Nail involvement
  • Onycholysis
  • Thickness of nail plate
  • Subungual hyperkeratosis

Seal and protect the nail

Nuvail changes the microenvironment of the nail bed, making it inhospitable to fungi. Once applied, Nuvail forms a barrier that is moisture-resistant, yet breathable. By creating an adverse environment for fungal growth, a healthy nail can regrow and prevent/reduce the chance of a future infection.³


  • Penetrates intercellular spaces and nail surface ridges²
  • Creates a stable, yet flexible molecular structure within the nail plate²
  • Generates mechanical support²
  • Protects against harmful effects of moisture²


  • Non hydrosoluble: hydrophobic molecule maintains proper moisture balance²
  • Breathable: allows for oxygen transfer to germinal matrix for optimal keratin formation²
  • Keeps up a good defense

Has high affinity to keratin structures:³

  • Improves overall nail appearance³
  • Promotes a more even, uniform nail plate³
  • Protects the nail from environmental factors²
  • Continues to work after application and does not wash off²

Prescribe First, Prescribe Often

A first-line treatment for all nail dystrophies.

Nuvail is patient friendly:³

  • No age restriction²
  • No duration restriction²
  • Drug-free prescription device³
  • Seconds to apply, minutes to dry²
  • Can use alone (goes on clear) or under polish²


Additional damaged nail resources:


  1. van der Kerkhof P, Pasch MC, Scher RK, Kerscher M, Gieler U, Haneke E and Fleckman P. Brittle nail syndrome: A pathogenesis-based approach with a proposed grading system. J Am Acad Dermatol. 2005;53:644-651
  2. Nuvail (poly-ureaurethane, 16%) NAIL SOLUTION [Prescribing Information]. Innocutis, Charleston, SC, 29401 USA; June 2012.
  3. Nasir A, Goldstein B, van Cleef M and Swick L. Clinical Evaluation of safety and efficacy of a new topical treatment for onychomycosis. J Drugs Dermatolo. 2011; 10(10):1186-1191.


Nuvail™ (poly-ureaurethane, 16%) NAIL SOLUTION is indicated for managing signs and symptoms of nail dystrophy, i.e., nail splitting and nail fragility, for intact or damaged nails. Nuvail coats and adheres to the nail surface preventing direct abrasion and friction on the nail surface while also providing protection against the effects of moisture.


Do not apply directly to deep, open, or profusely bleeding wounds. Product is flammable in liquid form; avoid using near open flames and sources of ignition. Use in a well-ventilated area.

Keep out of reach of children.

Store at room temperature away from heat. Do not allow product to come into contact with floors, counter tops, furniture or other finished surfaces – will stain. May temporarily sting upon application. Persons sensitized to isocyanate should not use this product. Should redness or other signs of irritation appear, discontinue use and consult your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Click here for Full Prescribing Information.